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Because the drug acts on gut hormone receptors and slows gastric emptying, the most commonly reported adverse effects in Phase 2 trials include: Nausea (particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally described as mild to moderate in severity and tended to diminish over time

Regular long-term follow-up is crucial to confirm the durability of this favorable outcome

Weeks 5 through 8: If you tolerate the starting dose well, your provider may increase you to 0.5 mg once per week

J., Zhang, V., Gratzl, S., Do, D., Goodwin Cartwright, B., Baker, C., Gluckman, T