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MNs penetrate the stratum corneum and precisely deliver drugs to the subcutaneous WAT to induce its browning, exerting effective action at the target site, significantly reducing systemic side effects and improving therapeutic outcomes

When used correctly and in appropriate doses, it presents very few side effects and provides real, measurable benefits

Results do vary between individuals, and treatment should be reviewed at 12 weeks if less than 5% weight loss has been achieved at the full 3 mg dose

For patients on strict dosing schedules, liposomal is often more practical, though both forms work when properly timed