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Moreover, FOXO4-DRI was used to selectively induce apoptosis of senescent fibroblasts in both keloid fibroblast and organ culture senescent models, showing potential as a treatment that targets the senescence and apoptosis resistance observed in keloid fibroblasts

Medications that slow gastric emptying, sulfonylureas, or insulin may require dose adjustments or additional monitoring when combined with GLP-1 therapy