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Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms

HELPS WITH REDUCE HAIR LOSS Hair loss is so common in men, that a B12 deficiency as the cause of it is often missed

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At Minnesota IV Hydration, B-complex vitamins are commonly included in energy-supportive infusions and may be added to other IV formulations when clinically appropriate